Name | Flumetralin |
Synonyms | CAG 41065 FLEXSHIELD Flumetralin Flumetralim FLEXIBLE PRIMER Flumetralin E.C. LEADING EDGE CHIP PRIMER N-(2-chloro-6-fluorobenzyl)-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline N-[(2-Chloro-6-fluorophenyl)methyl]-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline 2-Chloro-6-fluoro-N-(2,6-dinitro-4-(trifluoromethyl)phenyl)-N-ethylbenzenemethanamine Benzenemethanamine, 2-chloro-N-[2,6-dinitro-4-(trifluoromethyl)phenyl]-N-ethyl-6-fluoro- |
CAS | 62924-70-3 |
InChI | InChI=1/C16H12ClF4N3O4/c1-2-22(8-10-11(17)4-3-5-12(10)18)15-13(23(25)26)6-9(16(19,20)21)7-14(15)24(27)28/h3-7H,2,8H2,1H3 |
Molecular Formula | C16H12ClF4N3O4 |
Molar Mass | 421.73 |
Density | 1.5019 (estimate) |
Melting Point | 102 °C |
Boling Point | 223.5°C (rough estimate) |
Flash Point | >100°C |
Vapor Presure | 1.25E-08mmHg at 25°C |
pKa | -2.63±0.50(Predicted) |
Storage Condition | 2-8℃ |
Refractive Index | 1.581 |
Physical and Chemical Properties | The neat is a yellow or orange crystalline solid. m.p.101 ~ 103 ℃, relative density 1.55(20 ℃), vapor pressure <1.33 × 10-3Pa) (20 ℃), volatility <0.01mg/m3. Room temperature solubility: dichloromethane> 80%, methanol 25%, benzene 55%, hexane 1.3%, Water <0.1mg/L. 250 degrees C decomposition. |
Use | Used as a plant growth regulator, is a tobacco specific inhibitor |
Risk Codes | R36/38 - Irritating to eyes and skin. R43 - May cause sensitization by skin contact R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R67 - Vapors may cause drowsiness and dizziness R66 - Repeated exposure may cause skin dryness or cracking R36 - Irritating to the eyes R11 - Highly Flammable |
Safety Description | S36/37 - Wear suitable protective clothing and gloves. S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S16 - Keep away from sources of ignition. S9 - Keep container in a well-ventilated place. |
UN IDs | UN 1090 3/PG 2 |
RTECS | DA4391600 |
HS Code | 29214300 |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
toxicity | rat acute oral LD50>5000mg/kg, rabbit acute percutaneous LD50>2000mg/kg, acute inhalation of LC50>21.3mg/L in rats. Has a stimulating effect on the skin and eyes. No teratogenic and mutagenic effects. Rainbow trout LC50>3.2 μg/L(48h), Daphnia LC50>2.8 μg/L, quail acute oral LD50>2000mg/kg, wild duck LD50>2000mg/kg, acute Oral LD500.075 ~ 5 μg/Bee, no toxic effect was found. |
Use | high-efficiency tobacco lateral bud inhibitor of contact and local inhalation of this strain. It can be used for copying tobacco, sun-cured tobacco and cigar tobacco. The occurrence of tobacco axillary bud can be inhibited by applying the medicine once after topping. The dosage of 22.5~26.3g active ingredients/100 m2, fast absorption, rapid action, 2H after the application of no rain can be effective, and can make the natural maturity of tobacco leaves consistent, improve the quality of tobacco leaves, reduce field mosaic disease of contact infection. as a plant growth regulator, it is a special tobacco bud inhibitor |
production method | preparation of n-ethyl-2-chloro-6-fluorobenzylamine 79.3G of 2-chloro-6-fluorobenzaldehyde, 250ml methanol and 34g ethylamine. The imine was formed by controlling the temperature at 20-25 ° C. And the reaction time at 0.5-1H. 10-11g of sodium borohydride was added in portions to keep the temperature at 20-25 ° C., and the reaction was followed by gas chromatography. When the imine is completely converted into Amine, methanol is distilled off, 300ml of water and 50ml of dichloromethane are added, the organic phase is separated, the aqueous layer is extracted with dichloroethane, the organic phases are combined and desolvated, 93g of n-ethyl-2-chloro-6-fluorobenzylamine was obtained with a content of 94%-96% and a yield of 93%-95%. Synthesis of flurodiamine 97g of n-ethyl-2-chloro-6-fluorobenzylamine was added to a solution of 135.2G of 4-chloro-3, 5-dinitrotrifluorotoluene and 200ml of toluene, water 75ml, 40g of 50% NaOH was heated to 80 ℃ for 2H, and the reaction was followed by gas chromatography. When 4-chloro-3, 5-dinitro-1-trifluorotoluene <0.5%, the organic layer was dissolved in vacuum, and the melt was crystallized on an aluminum plate to obtain 210-215g of Fluor, the content of which was 96%-98%, and the yield was 94.8%. The reaction of 2-chloro-6-fluoro-ethylbenzylamine with 2, 6-dinitro -4-trifluoromethyl chlorobenzene gives fluoronamide. |
category | pesticide |
toxicity grade | poisoning |
Acute toxicity | oral-rat LD50: 3100 mg/kg |
flammability hazard characteristics | flammability; Toxic nitrogen oxides, fluorides, and chloride gases from combustion |
storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials |
extinguishing agent | dry powder, foam, sand |